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J Zhejiang Univ Sci B 21(12):990998 Oduro PK, Zheng X, Wei J, Yang Y, Wang Y, Zhang H et al (2022) The cGAS-STING signaling in cardiovascular and metabolic diseases: future novel target option for pharmacotherapy

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Interestingly, the closest relatives of many mtDNA-modifying enzymes, such as mtDNA polymerase, are bacteriophage proteins [94], suggesting that an infection of the mitochondrial ancestor contributed to the development of mtDNA maintenance machinery

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