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For example, glycine N-methyltransferase (GNMT), an enzyme that reduces the SAM/SAH ratio, is inhibited by 5-methyltetrahydrofolate (5-mTHF) ( DNA methylation and demethylation pathways DNA methylation is catalyzed by DNA methyltransferases (DNMTs), which transfer methyl groups from SAM to cytosine bases at their fifth carbon (C-5)

Although these numbers show slight improvement over earlier years, vaccination rates in the United States are much lower than they are in other developed countries such as Australia where high uptake (above 70 percent) is predicted to eliminate cervical cancer as a public health concern within the next 20 years (126)

Valla et al., 2010)

5K-L, Supplementary Fig