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A prospective cohort study at the National University of Singapore with over 600 participants aged 60 and above showed that individuals who consumed more than two servings of mushrooms per week had a 57% reduced prevalence of mild cognitive impairment (MCI) even after controlling for age, sex, education, hypertension, diabetes, and physical activity

The diminished leptin levels invigorate the hypothalamus, subsequently increasing appetite and stimulating food intake behaviors

Furthermore, the treatment with NMN resulted in a significant upregulation of adipose triglyceride lipase (ATGL) expression in subcutaneous fat, which is in line with the observed alterations in fat mass and adipocyte size (Imi et al., 2023)

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