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To minimise scoring variations, three trained team members independently evaluated the myopathies

Nature 474:327336

Aerosolized phosphoinositide 3-kinase gamma/delta inhibitor TG100-115 [3-[2,4-diamino-6-(3-hydroxyphenyl)pteridin-7-yl]phenol] as a therapeutic candidate for asthma and chronic obstructive pulmonary disease

Same phenomenon is observed in the presence of Cys and Hcy, indicating a chemical reaction may take place between TPE-DCV and thiols which breaks down the conjugation of TPE-DCV