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doi: 10.2119/200600086.Lee 5 LeeHCDengQWZhaoYJ

Despite the evidence of the significance of Leiden mutation, the effect of this hematological disorder in the etiology of RVO is only marginal.21 In recent studies of patients with RVO, no significant association with a deficiency of antithrombin or with prothrombin mutation was found.21,26,34,3740 Antiphospholipid antibodies (APA) consist of a heterogeneous group of immunoglobulins, mainly anti-cardiolipin antibodies (ACA) and lupus anticoagulants (LA)