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2014), while ajoene halts the cycle at G2/M and induces apoptosis in HL-60 cells (Powolny and Singh 2008)

& McGettigan, S

Evidence suggests that IFN- suppresses System Xc transcription by activating the JAK-STAT-IRF1 pathway, which depletes intracellular GSH stores, intensifies lipid peroxidation, and induces ferroptosis in various tumor and immune cells