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Injection Method

490 Excessive inhibition of Nrf2 may not improve DOX-induced cardiomyopathy due to insufficient promotion of antioxidant gene expression, while its overactivation increases the breakdown of heme and ferrous iron levels in the HO-1-catalyzed manner, promoting ferroptosis

Jayakumar S, Jennings S, Halvorsrud K, Clesse C, Yaqoob MM, Carvalho LA, et al