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Although it has protective antioxidant functions, its surge may also alter copper kinetics, potentially increasing the delivery of redox-active copper to tissues or disrupting its cellular utilization, thereby paradoxically exacerbating copper-mediated toxicity in cardiomyocytes [177]

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Lactobacillus -mediated weight loss may be brought about, at least in part, by changes to lipid absorption and triglyceride synthesis, since orally-administered Lactobacillus rhamnosus GG reduces intestinal lipid absorption and the expression of triglyceride synthesis-related genes in mice 98

Consistent with this, BDNF release from astrocytes was also shown to be induced by elevated extracellular potassium concentration (Stahlberg et al