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Their mobility and bioavailability are a significant concern globally owing to plant uptake and increased human exposure to these HMs by eating contaminated foods (Mapodzeke et al., 2021)

39 Although various signaling pathways involve in the regulating of hair follicle generation and hair growth, such as Keap1-Nrf2 pathway, 40 Akt--Catenin pathway, 40 NF-B 29 and MAPK, 16,41,42 et al