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Because roGFP2-Orp1 undergoes a specific H 2 O 2 -dependent oxidation, but can also be reduced, its redox state is influenced either by the level of the oxidant (H 2 O 2 ) or by the reductants themselves, such as GSH and thioredoxin [15]

GSH, a tripeptide composed of glycine, cysteine, and glutamic acid, is a pivotal hub in cellular defense, functioning as both a primary antioxidant and a crucial regulator of copper ion bioavailability [105]

At the same time, the structure of liposomes is similar to cell membranes, which makes it easier to fuse with or be taken up by intestinal mucosal cells

PGZ was well tolerated in F3 progressors