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What If: FOXO4-DRI Timing Scenarios What If I Can't Maintain an 8-Hour Fast Before Morning Dosing

Stop DFP/DFX 3/12 before conception, switch to DFO For females: Joint management of pregnancy and increased risks: cardiomyopathy, osteoporosis, haemosiderosis off-chelation, diabetes (risk for foetus), osteoporosis, infection Review by cardiologist at 28/40 gestation Can re-start DFO from second trimester and continue through breast-feeding (not DFP or DFX) See also: thalassaemia pregnancy management plan

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Additional information Peer review information Nature Communications thanks David Binks and the other, anonymous, reviewer(s) for their contribution to the peer review of this work