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Bo et al

1 Introduction Phytochemicals, a diverse group of bioactive compounds found in plants, are the subject of renewed interest in biomedical research for their chemopreventive and chemotherapeutic properties (George et al., 2021

Because typical early atherosclerotic lesion formation observed in hyperhomocysteinemic animals can be prevented by an antiplatelet therapy with dipyridamole, the authors concluded that platelet-mediated proliferation of smooth muscle cells is a potential cellular mechanism involved in the atherogenicity of hyperhomocysteinemia

It also activates protective signaling pathways such as AhR/PXR, thereby exerting synergistic regulatory effects at the microbiotametabolism interface ( Regarding safety, the combination therapy generally exhibited a favorable tolerance profile