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This suggests that targeted pharmacologic or biologic modulation of these pathways could mitigate NPPC depletion and bolster their innate regenerative capacity, effectively transforming the diseased microenvironment from an inhibitory into a supportive one

Ebselen attenuates cisplatin-induced ROS generation through Nrf2 activation in auditory cells

Conflicts of Interest The authors have nothing to disclose regarding the work under consideration for publication

Although no abnormality in the genital tract has been reported for heterozygous mice, transgenic male mice that express higher levels of Mn-SOD are infertile but the mechanism for this is unknown [9]