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Zonder adequate bescherming tijdens de passage door het spijsverteringsstelsel kan een deel van de stof worden afgebroken voordat deze wordt opgenomen

rather, we would base the payment limit of the biosimilar on the volume-weighted average of the its own most recently available positive manufacturer's ASP data from a previous quarter and either 6 or 8 percent, as appropriate, of the amount determined under section 1847A(b)(4) of the Act for the reference biological product for the given quarter

Their amphiphilic architecture enables the sequestration of poorly water-soluble compounds within a hydrophobic core, while maintaining aqueous stability

Rotary evaporation was used to yield the crude product, which was dissolved in water and titrated to pH 7.2