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RA-FLSs have tumor cell-like anti-apoptotic characteristics, and inhibition of their proliferation and migration has been the focus of attention in RA therapy

GhGPX6, 810, 12 were grouped into clade I, GhGPX1, 3, 5 into clade II and the GPXs in sub-classification of clade II, including GhGPX1, PtGPX1, AtGPX1, 7 and OsGPX6, 8 were all predicted to have the subcellular localisation of the chloroplast or mitochondria (Table 4)

364,365 Besides, aberrant mitophagy triggered by PINK and Parkin mutations are associated with PD development in familial PD patients

These mitochondria are also the site of significant oxidative stress