The use of the in vitro comet assay with liver cell models can already be considered as part of an overall weight of evidence approach, but further optimization work, including expanded training sets of compounds and thorough validation of appropriate and ubiquitously available liver cell models would be required, before it could be incorporated into a standard battery for genotoxicity testing of NAs
Diabetic peripheral neuropathy progression remains the most common explanation for numbness in this patient population

E-Posters - DIAGNOSIS / ETIOLOGY 04.00 - DIAGNOSIS / ETIOLOGY - 04.06 - CARDIOEMBOLISM & HEART-BRAIN INTERACTIONS P2339 - ESOC25-455 UNSUPERVISED CLUSTER ANALYSIS OF TRANSTHORACIC ECHOCARDIOGRAPHY PARAMETERS REVEALS DISTINCT PHENOTYPES IN ACUTE ISCHEMIC STROKE PATIENTS RECEIVING INTRAVENOUS THROMBOLYSIS AND ASSOCIATES WITH CLINICAL OUTCOMES Yue Ting Tang 1 , Aloysius Leow 2 , Chun En Yau 2 , Leonard Yeo 2,3 , Ching Hui Sia 2 , Benjamin Tan 2,3 1 Department of Geriatric Medicine, Khoo Teck Puat Hospital, National Healthcare Group, Singapore, Singapore, 2 Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, 3 Division of Neurology, Department of Medicine, National University Hospital, Singapore, Singapore Background and Aims: Transthoracic echocardiography (TTE) performed during acute ischemic stroke (AIS) provides insights into heart-brain interactions
The peptides stay cold enough