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Description

Since the synthesis and expression of GPx4 are regulated by various cellular processes, targeting GPx4 may constitute a promising strategy for the induction of ferroptosis and the promotion of cancer cell death in treatment-resistant cancers (Lee and Roh 2023)

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Protein and membrane visualizations were created using VMD and PyMOL

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MDA, ROS) and modulated innate immune signaling by upregulating TLR4 expression yet simultaneously inhibiting NF-B activation

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Dec 2000;29(4):295-301

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