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Feature · Product Review
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The efficacy of ADCC and CDC, and consequently response rates observed in GEN501 and SIRIUS trials, are directly proportional to CD38 expression levels on MM cells

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(6) less enzymatic degradation

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[DOI] [PMC free article] [PubMed] [Google Scholar] 55.Buhl R., Jaffe H.A., Holroyd K.J., Wells F.B., Mastrangeli A., Saltini C., Cantin A.M., Crystal R.G

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anti-estrogens including, for example, tamoxifen, raloxifene, aromatase inhibiting 4(5)-imidazoles, 4-hydroxytamoxifen, trioxifene, keoxifene, immunosuppressive agents include, but are not limited to 2-amino-6-aryl-5-substituted pyrimidines, azathioprine, cyclophosphamide, bromocryptine, danazol, dapsone, glutaraldehyde, anti -idiotypic antibodies for MHC antigens and MHC fragments, cyclosporin A, steroids such as glucocorticosteroids, cytokine or cytokine receptor antagonists (e.g., anti-interferon antibodies, anti-ILlO antibodies, anti-TNFa antibodies, anti-IL2 antibodies), streptokinase, TGFP, rapamycin, T-cell receptor, T-cell receptor fragments, and T cell receptor antibodies

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