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Description

HMGB1 mediates synaptic loss and cognitive impairment in an animal model of sepsis-associated encephalopathy

Protein Cell 12 , 346359 (2021)

This activation induces the transcription of antioxidant response element (ARE)-regulated genes, including heme oxygenase-1 (HO-1), SOD, catalase, and glutathione peroxidase