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9,10 Acetylcysteine, used in treating acetaminophen toxicity, is a substrate for glutathione synthesis and ultimately increases the amount of glutathione available to bind NAPQI and prevent damage to hepatocytes

These findings show that AS3MT automethylation is governed by at least four cysteines C33, C62, C157, and C207, which are the same residues needed to catalyze arsenic methylation