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Adipose-Derived mesenchymal stem cell secretome attenuates prion protein peptide (106126)-Induced oxidative stress via Nrf2 activation

124,125 Oxidation induces conformational changes, enhancing dissociation rates, particularly in the C-terminus of Ku80, which contains Cys493 and Cys638 and is crucial for DNA-PKcs recruitment

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[0510] Regardless of the route of administration selected, the antibodies and/or immunoconjugates described herein, that may be used in a suitable hydrated form, and/or the pharmaceutical compositions, are formulated into pharmaceutically acceptable dosage forms by conventional methods known to those of skill in the art