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There is a dynamic interplay of pulsatile GHRH and somatostatin secretion: Via crosstalk : GHRH neurons receive inhibitory inputs from somatostatin neurons, whilst somatostatin neurons receive direct stimulatory inputs from GHRH neurons Via synergistic actions on somatotrophs : Pre-exposure to somatostatin enhances GHRH-stimulated secretion of GH (457)

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Regardless, the primary reasons for the strong acclimation across space in the current climate and increased resilience across time should be paramount research priorities going forward so that public resources can be best allocated towards the causes that most effectively increase adaptation and resiliency as the climate warms