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Participants Twelve women between the ages of 39 and 76 years with a mean age of 58.3 years participated in this trial at a private clinic

Moreover, lactate-mediated H3K18 lactylation positively regulates the transcription of tumor necrosis factor superfamily member 9 (TNFSF9), further linking lactate metabolism with M2 polarization events [171]

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Recent studies delivered proof of the notion that disrupting VEGF/VEGFR-2 signaling could improve the effectiveness of the ACT in tumor model [142]