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Macrophages, as key effector cells of the innate immune system, play multifaceted and central roles in this process, including immune complex clearance, antigen presentation, inflammation regulation, and tissue repair and fibrosis ( The aberrant activation of the glycolytic pathway serves as a key engine driving the inflammatory response of macrophages in LN

Clinically, this connection between mycotoxins and mast cell activation may help explain why patients with chronic mold exposure often present with a constellation of symptoms, including brain fog, fatigue, light sensitivity, anxiety, and histamine intolerance, even when traditional testing is unremarkable 13

Kolodziej et al., 2017)