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Eventually, the activated effector caspases will cleave a large number of cellular substrates, leading to typical apoptotic phenotypes: chromatin condensation, DNA fragmentation, cell shrinkage, and membrane blebbing [37]

In adult cats, infection leads to a transient decrease in the immune response: neutrophil counts decrease severely, and lymphocytes disappear from the circulation, lymph nodes, bone marrow and thymus (Pedersen, 1987