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Zhao W, Yao Z, Cao J, Liu Y, Zhu L, Mao B, et al

Topicals reduce melanin production at the surface over weeks Peels & microdermabrasion exfoliate pigmented surface cells Laser breaks up deeper melanin deposits Antioxidants support even tone

Starting with tirzepatide injection and optionally adding genetic testing ensures evidence-based, individualized therapy rather than off-label polypharmacy