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Researchers should note that clinical studies on Fragment 176-191 to date have not involved administration via subcutaneous injection, but have employed infusion instead, as four escalating single doses of 25mcg 400mcg/kg, with a washout week between each administration [1]

In severe cases, some neurological complications may become permanent if treatment starts too late

Nerve damage and slow signals : B12 is key for nerve insulation (myelin)