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The factor responsible turned out to be a small copper-binding tripeptide whose endogenous concentration declines with age from roughly 200 ng/mL at age 20 to 80 ng/mL at age 60. The 50-year research arc that followed makes GHK-Cu one of the most thoroughly characterized small peptides in the literature

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Omics-based novel strategies in the diagnosis of endometriosis Crit Rev Clin Lab Sci 61 3 205 25 N Bresgen PM Eckl 2015 Oxidative stress and the homeodynamics of iron metabolism Biomolecules 5 2 808 847 N Halim E ChNg E Kardia S Ali R Radzi B Yahaya 2019 Aerosolised mesenchymal stem cells expressing angiopoietin-1 enhances airway repair Stem Cell Rev Rep 15 112 25 P Parasar P Ozcan 2017 Terry KLJCo, reports g Endometriosis: epidemiology, diagnosis and clinical management Curr Obstet Gynecol Rep 6 34 41 P Vercellini P Vigan E Somigliana L Fedele 2014 Endometriosis: pathogenesis and treatment Nature Rev Endocrinol 10 5 261 75 P Vigan F Caprara F Giola G Stefano Di E Somigliana 2021 Vercellini PJHRO Is retrograde menstruation a universal, recurrent, physiological phenomenon

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