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doi: 10.1021/tx049675w

[DOI] [PubMed] [Google Scholar] 33.Muller TD, Finan B, Bloom SR, DAlessio D, Drucker DJ, Flatt PR, et al

Others, after conducting their own stability testing, extend to 60 or even 90 days

These modifications include an Ala8Aib amino acid substitution and attachment of a C18 fatty diacid side chain at Lys26 via a linker that promotes albumin binding, significantly prolonging circulation time compared to native GLP-1