foxo4-dri senolytic peptide human trial 2024 2025 alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice The disordered p53 transactivation domain
The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications Senescent cells as a target for anti aging interventions: From senolytics to immune therapies PMC Cellular Senescence in Health, Disease, and Lens Aging (PDF) Senolytic Peptide FOXO4 DRI Selectively Removes Senescent Cells From in vitro Expanded Human Chondrocytes
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