b12 injections change skin problems Hyperpigmentation as a Primary Symptom of Vitamin Deficiency: A Case Report The Impact of Vitamin B12

Acknowledgments We thank Dr Alireza Emami Naiieni and Dr Morteza Pourahamd for their comments in final editing of the manuscript

25 More recent studies have also linked vitamin D deficiency to sickle cell disease, aromatase inhibitorinduced arthralgia, headache, PHN, pain in patients taking high doses of opioids, and various types of musculoskeletal and orthopedic pain

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Briefly, samples collected from each group were affixed to silica wafers (1 cm 1 cm) with the sample holder temperature setting at 60 C