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Two micrograms of total RNA were reverse transcribed into complementary DNA (cDNA) using Reverse Transcription kit (Vazyme, Nanjing, China)

elegans with a high degree of homology to the human MRP-1 protein 33 , and glutathione homeostasis in defense against pathogen infection

Commonly encountered drugs that interact with DAAs include antiarrhythmic drugs such as amiodarone, antiepileptic and barbiturate drugs (e.g., carbamazepine, oxcarbazepine, phenobarbital, and phenytoin), antipsychotic medications, antituberculosis drugs (e.g., rifampin and rifapentine), anticoagulant medications, and antidiabetic agents [64]

The endogenous substrate for this is cysteamine and it can oxidize the nucleophilic sulphur and nitrogen atom (Porter, 2002)