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The copper delivery hypothesis proposes that GHK-Cu regulates intracellular copper levels, which in turn affect copper-dependent transcription factors and enzymes

In one review paper, the authors state the following: Glutathione (GSH) plays an important role in a multitude of cellular processes, including cell differentiation, proliferation, and apoptosis, and as a result, disturbances in GSH homeostasis are implicated in the etiology and/or progression of a number of human diseases, including cancer, diseases of aging, cystic fibrosis, and cardiovascular, inflammatory, immune, metabolic, and neuro-degenerative diseases

An operon encoding a putative Ln chelator has been identified in Methylorubrum extorquens AM1 (Roszczenko-Jasiska et al., 2020)