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Multiple trials have robustly shown a strong association of NNMT with IR and T2D (Kraus et al., 2014

Other foods that contain vitamin B12 include fish (particularly oily fish like salmon, trout, mackeral) and seafood (like oysters, clams), and dairy products (milk, yoghurt, cheese) are good sources of vitamin B12, but it is important to note that content can vary based on degree of processing and fortification (or lack of fortification) (7-9)

Rev Med Virol 25:224240 Nasiri K, Mohammadzadehsaliani S, Kheradjoo H, Shabestari AM, Eshaghizadeh P, Pakmehr A, Alsaffar MF, Al-Naqeeb BZT, Yasamineh S, Gholizadeh O (2023) Spotlight on the impact of viral infections on Hematopoietic Stem Cells (HSCs) with a focus on COVID-19 effects

Moreover, probiotics also regulate immune response through their interaction with immune cells in gut-associated lymphoid tissue (GALT), enhance immune tolerance, and suppress chronic inflammation (Ballini et al., 2023)