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Other factors, such as the upregulation of immune checkpoint molecules, including programmed death-ligand 1 (PD-L1) and programmed cell death protein 1 (PD-1), also suppress the immune system (361)

Furthermore, a recent study investigating patients with psoriatic arthritis (PsA) demonstrated that various biologic agents including infliximab, adalimumab, etanercept, golimumab, certolizumab, ustekinumab, and secukinumab were associated with an overall protective effect against liver fibrosis in individuals with MASLD

The total effects of the met-a-308, met-a-337, and met-a-584 instrumental variable sets did not show significant deviations