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The group also discovered that stopping the GCPII from being active by using a drug called 2-PMPA to treat human ovarian tumors implanted in ovaries of mice, reduced tumor weights and glutamate concentrations

Ann Oncol 20:736740 Monk B, Kauderer J, Moxley K, Bonebrake AJ, Dewdney SB, Secord AA, Ueland FR, Johnston CM, Aghajanian C (2018) A phase II evaluation of elesclomol sodium and weekly paclitaxel in the treatment of recurrent or persistent platinum-resistant ovarian, fallopian tube or primary peritoneal cancer: an NRG oncology/gynecologic oncology group study

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Identification of DMeHg from the exhaled breath of mice Since DMeHg is a volatile material with a high vapor pressure (8.8 kPa at 20 C, reference from ICSC), we confirmed whether DMeHg derived from (MeHg) 2 S was distributed in the lung and then exhaled outside of the body