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PC2 score plot for all the samples, however, the PCA distribution did not identify a valid separation between the HC and ASD groups

Cuproptosis can modulate the expression of key genes involved in ferroptosis regulation, such as glutathione peroxidase 4 (GPX4), by eliminating phospholipid hydroperoxides [123, 124] and acylcoenzyme A synthetase long-chain family member 4 (ACSL4) [125], thereby regulating the sensitivity of cells to ferroptosis inducers

Parents rated intervention response using a modified Clinical Global Impression Improvement type scale called the Parent Rated Autism Symptomatic Change (PRASC) scale

doi: 10.1038/s41419-021-03872-9 400 MakkiKFroguelPWolowczukI