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While donor smoking history was linked to a statistically significant reduction in forced expiratory volume in 1 second (FEV1) in double lung transplant recipients one year after transplant, this effect was not clinically significant. The number of donor lungs available for transplantation is limited, which makes it crucial to strike the right balance between avoiding unnecessary limits on the donor pool and still identifying the most suitable donors

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Furthermore, Firmicutes, Bacteroidetes and Actinobacteria were enriched at all lower taxonomical levels in CS, being characterized at the genus level among others by Megasphaera and Dialister (Firmicutes), Paludibacter , Porphyromonas and Prevotella (Bacteroidetes), and Atopobium (Actinobacteria)