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ECMs are diminished and proliferation of HSCs and Kupffer cells is inhibited via the TGF-/Smad pathway

While forming the dimeric structure, domain I of one subunit and domain II of the second interact with each other by the lock-and-key principle

Anthocyanins from purple sweet potato attenuate dimethylnitrosamineinduced liver injury in rats by inducing Nrf2mediated antioxidant enzymes and reducing COX2 and iNOS expression