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5061, PMID 6443144, archived from the original (PDF) on 17 October 2016, retrieved 29 March 2016 "Construction of cigarettes and cigarette filters"

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However, epidemiological studies assessing Swedish smokeless tobacco, which exposes users to nicotine without combustion products, generally have not found an increased risk of myocardial infarction or stroke among users, but suggest that nicotine might contribute to acute cardiovascular events, especially in those with underlying coronary heart disease