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Most of the chemicals that cause smoking-related diseases are absent in e-cigarettes and the current best estimate is that e-cigarette use is around 95 percent less harmful to health than smoking, the study said

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The letters did not order Reynolds to recall its products, or explicitly threaten any fines or legal action against the company, but the notice could drastically cut into Reynolds sales because it would open up retailers to fines if they sell the products

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