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In addition, our results were still significant when we compared the non-age-matched groups, including younger patients who smoked marijuana and who presumably had less lifetime exposure to cigarette smoke. According to the CDC, 48.2 million people, or about 18% of Americans, used marijuana at least once in 2019

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Smoking has been identified as an independent predictor of total testosterone levels, even after adjusting for factors such as age, BMI, fasting blood glucose, triglycerides, alcohol consumption, and estradiol