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The First Week: Riding the Wave of Withdrawal This period is often the most physically challenging due to nicotine withdrawal, but its also when some of the most noticeable positive changes begin

Furthermore, smoking may also result in direct damage to fetal genetic material 6 , impaired lung development 7 , acceleration of fetal heart rate and a reduction in fetal breathing movement

We based our recommendations on an overview of Cochrane reviews on smoking cessation interventions;22 certainty of effects is described in Appendix 1, available at www.cmaj.ca/lookup/doi/10.1503/cmaj.241584/tab-related-content

This leads to the formation of an aerosol consisting mainly of the water, VG, nicotine, and flavors contained in the tobacco substrate