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2,3-Butanedione has been linked to a rare but severe lung disease called bronchiolitis obliterans, which is also known as popcorn lung, a term adapted when popcorn factory workers acquired the disease after being exposed to high levels of the vaporized substance

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These conditions may impair cardiovascular reserve and limit compensatory responses to hemodynamic stress, ultimately leading to increased pulmonary artery pressures and pulmonary edema [28]

The state was also set to increase the required thickness of plastic bags from 2.25 mils to 4 mils on Jan