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Despite the effectiveness of population-based government programs, such as education on the dangers of tobacco and cigarette advertising restrictions, evidence suggests that stricter rules and more precise implementation strategies are needed to achieve long-term goals

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The existing totality of evidence suggests an urgent need to increase the use of varenicline in the general population as well as in those with serious mental illness who on average die about 20 years earlier than the general population, in part, because their smoking rates may be as high as 75 percent, said Hennekens