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Commercial sales became important in the late 19th century, as major tobacco companies arose in the South, becoming one of the largest employers in Winston-Salem, North Carolina, Durham, North Carolina, and Richmond, Virginia

12A.5.1.1 Implementation studies Shortly before the implementation date for new graphic health warnings in 2006, one tobacco manufacturer sold products in retro-tins from which the label could easily be removed ( Figure 12A.5.2 )

One has a hinged lid and one contains a tortoise shell comb