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According to the National Institute on Drug Abuse, Among people aged 12 or older in 2020, 1.9% (or about 5.2 million people) reported using cocaine in the past 12 months.[2] Cocaine is a potent stimulant drug that causes a fast and energetic high that people become addicted to rather quickly

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Smoking remained common in the military, with the rate of smokers staying consistently above the rate of civilian smokers until overall cigarette use began to decline in 2011

In addition, E2/P imbalance, known as the unopposed estrogen hypothesis, negatively affects embryo implantation and has been used as a predictor in the outcome of assisted reproductive techniques [9, 10]