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Five Topmost Addictive Substances in the World Vaping: What Parents Need to Know Vaping isn't harmless it's a serious concern. Most vape products contain nicotine, a highly addictive substance that can impact developing brains and overall health. Quitting Smoking The nicotine in tobacco is a highly addictive substance that makes people dependent on the product. This is dangerous because tobacco use is a major risk factor for many cardiovascular and respiratory
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