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The latest data for e-cigarette use by Kentucky teens, from 2018, shows e-cig use had nearly doubled since 2016, with more than one in four high-school seniors and one out of seven eighth-graders reporting they used the devices, the Kentucky Incentives for Prevention study found

Interestingly, long-term nose-only exposure for 1 month caused a significant increase of ROS in the heart accompanied with decreased heart GSH concentrations in exposed mice, indicating depletion of the antioxidant, which increases heart tissue's vulnerability to oxygen free radical damage [199]

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