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Probucol promotes low density lipoprotein (LDL) catabolism, inhibits ABCA1-dependent cholesterol efflux, and decreases HDL-C levels

Cardiovascular Benefits: Suppresses pro-inflammatory cytokines (IL-6, TNF-alpha) Reduces endothelial inflammation May stabilize vulnerable plaque Protects against immune-mediated vascular injury In patients with high PULS test scores or elevated CRP, KPV may offer a targeted anti-inflammatory intervention